Are you passionate about exploring protein-ligand interactions using cutting-edge biophysical methods? Join Orion Pharma and contribute to groundbreaking drug discovery!

Description of position

As a specialist in biophysics within our Structural Biology and Analytics unit, you will be at the forefront of utilizing techniques such as SPR, DLS, nanoDSF, TSA, and ITC. Your role will involve studying the kinetic and thermodynamic properties of protein-protein, and protein-ligand interactions.

This role is permanent and it is located in Espoo, Finland.

Description of unit

The Structural Biology and Analytics unit is part of the Medicine Design in Innovative Medicines Business Division. We provide analytical support for medicinal chemistry activities and focus on hit finding, understanding modes of action, and protein-ligand interactions. Our on-site capabilities include MS and NMR, are complemented by external collaborations for techniques like cryoEM and X-ray.

We offer

The position offers an exciting and challenging opportunity for cross-scientific and -cultural collaboration and working in highly motivated teams. You will have the chance to strengthen and build up our expertise of proteins and protein ligand interactions by using & building up our biophysical capabilities like SPR, DLS, nanoDSF, and TSA. Part of the work is naturally also done with research partners. We have a good working atmosphere based on common values and mutual trust. Please visit our website to find further information about our values and Orion as an employer https://www.orion.fi/en/careers/orion-as-an-employer/.

Requirements

Practical skills with biophysical methods especially SPR but also DLS, nanoDSF, and TSA are mandatory. Having utilized these techniques with membrane proteins or protein complexes or in studding covalent modulators is a big plus.

The candidate’s special focus will be execution of experiments and data analysis as well as communicating the results to the project team.

The candidate shall have a good knowledge of protein handling & production and must be able to discuss in multidisciplinary project teams the results and the impact of the results on drug design. A good network within the biophysical community around the world is a big plus.

A PhD degree in biochemistry, biophysics or a comparable discipline with working experience on biophysics is required.

Join us and make a significant impact on the future of drug discovery!

Additional information

Are you interested in this opportunity? Please send your application incl. salary request and CV by the 3rd November 2024. We will start reviewing applications during the application period.

For additional details, please contact Head of Structural Biology and Analytics Josef Messinger tel. +358 50 966 5287 on 16 & 18th October at 11.30-14.00  (Finnish time).

#LI-ORION

Approved medical examination which also includes drug testing is required prior to the employment. We will also carry out a security clearance prior to the employment for the selected person.


Orion Corporation operates in more than 30 countries, where we Orionees, 3600 in total, work in all kinds of positions. Among us there are Research Scientists, Laboratory Technicians, Engineers and IT Specialists as well as people working in Production, just to mention some examples. We offer diverse and responsible jobs to our personnel in a truly multi-disciplinary work environment. We encourage people to develop their competences and offer opportunities to affect the job description and creating their own career path at Orion. We are searching for top talents who are ready to share our passion for the work that we do.